Phenobarbital and carbamazepine enzyme inhibitors

C - Chemistry – Metallurgy – 07 – F

Patent

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260/256, 260/241

C07F 9/6512 (2006.01) C07F 9/40 (2006.01) C07F 9/553 (2006.01)

Patent

CA 1224783

ABSTRACT OF THE DISCLOSURE The present invention relates to novel conjugates of phenobarbital and carbamazepine which can be used as tracers for acetylcholinesterase in immunoassays for the determination of phenobarbital and carbamazepine in serum or plasma, said conjugates having the formula: Image wherein R2 is selected from the group consisting of: Image and Image and wherein Z is a biologically compatible counter ion, n and m are each independently an integer from 2 to 6, and R and R1 are each independently lower alkyl.

466225

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