Phenol derivatives and method of use thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 209/48 (2006.01) C07C 213/02 (2006.01) C07C 215/56 (2006.01) C07C 215/60 (2006.01)

Patent

CA 2491020

Novel phenol derivatives represented by the formula (1) [wherein the carbon atom indicated by (S) is of the S configuration and Z represents the group represented by the formula (2) or the formula (3) (wherein the carbon atom indicated by (R) is of the R configuration)]. They are useful as intermediates for various medicines. Also provided is a process for producing the phenol derivative represented by the formula (A) (wherein the carbon atoms respectively indicated by (R) and (S) have the same meanings as defined above) which comprises using any of those derivatives as an intermediate therefor.

L'invention concerne de nouveaux dérivés de phénol représentés par la formule (1) [dans laquelle l'atome de carbone indiqué par (S) présente une configuration en S et Z représente le groupe représenté par la formule (2) ou la formule (3) (dans laquelle l'atome de carbone indiqué par (R) présente une configuration en R)]. Lesdits dérivés sont utilisés comme intermédiaires dans divers médicaments. L'invention concerne également un procédé de production d'un dérivé de phénol représenté par la formule (A) (dans laquelle les atomes de carbone indiqués, respectivement, par (R) et (S) sont tels que définis ci-dessus), consistant à utiliser un quelconque de ces dérivés comme intermédiaire.

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