Phenothiazine compounds

Details Phenothiazine compounds Phenothiazine compounds

C - Chemistry, Metallurgy

07

D

167/214, 260/243

C07D 279/28 (2006.01) C07C 57/58 (2006.01) C07C 205/56 (2006.01) C07D 279/20 (2006.01) C07D 279/24 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 453/02 (2006.01)

Patent

CA 1280749

ABSTRACT Compounds of the formula (I): R4 Image (I) or salts, esters or amides, thereof, wherein R1 is a C1-7 bivalent hydrocarbon group or a single bond; R2 and R3 are the same or different and are each hydrogen, C1-4 alkyl or taken together with the nitrogen comprise a nitrogen-containing heterocyclic ring having four to six ring members; R4 is hydrogen, halogen, C1-4alkoxy, C1-4 alkyl optionally substituted by one to three halogen atoms; or a group R1 CO2H as hereinbefore defined and A is C1-4 alkylene or ANR2R3 forms a group Image or Image ; exhibit anti-allergic and anti- histaminic activity. Processes for preparing these compounds, novel intermediates in their preparation, pharmaceutical compositions containing the compounds, and the compounds for use in medicine are also described. AJR/KMS/DC11/03.11.83

442325

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