Phenothiazine derivatives, their production and use

Details Phenothiazine derivatives, their production and use Phenothiazine derivatives, their production and use

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) C07C 381/02 (2006.01) C07D 207/404 (2006.01) C07D 207/452 (2006.01) C07D 279/18 (2006.01) C07D 279/20 (2006.01) C07D 417/14 (2006.01) G01N 33/532 (2006.01) G01N 33/533 (2006.01)

Patent

CA 2067028

Abstract of the disclosure: PHENOTHIAZINE DERIVATIVES, THEIR PRODUCTION AND USE There is disclosed a novel phenothiazine derivative of the general formula (I): Image (I) wherein R1, R2, R3 and R4 are the same or different and are a C1-6 alkyl group and at least one of them has as a substituent a group which can react with amino group, thiol group or carboxyl group, and X- is a counter ion of the phenazathionium. Their production and the intermediates used in the production are aslo disclosed. The compound (I) is a derivative of methylene blue and is applicable to photodynamic therapy of cancer or immunoassays utilizing chemiluminescence.

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