C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/313, 260/314
C07D 231/00 (2006.01) C07C 43/23 (2006.01) C07D 231/12 (2006.01) C07D 231/14 (2006.01) C07D 231/16 (2006.01) C07D 231/56 (2006.01) C07D 233/64 (2006.01) C07D 235/06 (2006.01) C07D 249/02 (2006.01) C07D 249/04 (2006.01) C07D 249/18 (2006.01) C07D 521/00 (2006.01)
Patent
CA 1156661
ABSTRACT This invention provides compounds of the general formula Image (I) wherein R represents a lower alkyl group, X represents an oxygen or sulphur atom, n stands for zero or 1, Y represents a methylene, ethylene or propylene group or, when n stands for zero, Y can also represent a group of the formula - CH=CH-CH2 - (a) , in which the double-bond is trans and the carbon atom marked with an asterisk is linked to Z, and Z represents a 5-membered aromatic heterocyclic ring which contains one or more nitrogen atoms as the sole hetero atom(s), which is linked to Y via a nitrogen atom and which may be substituted by a halogen atom or a lower alkyl, lower alkoxy, aryl, cyano or carboxamido group or on adjacent carbon atoms by a group of the formula -(CH2)4- or -CH=CH-CH=CH- , (b) (c) and pharmaceutically acceptable acid addition salts thereof, a process for their manufacture and pharma- ceutical preparations containing them. The aforementioned compounds and salts possess .beta.-adrenersic blocking activity and antihypertensive activity.
369620
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
LandOfFree
Phenoxy-aminopropanol derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phenoxy-aminopropanol derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenoxy-aminopropanol derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-284644