Phenoxyacetic acid amide derivatives and their use in the...

C - Chemistry – Metallurgy – 07 – C

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C07C 237/04 (2006.01) A61K 31/16 (2006.01) C07D 217/04 (2006.01) C07D 295/185 (2006.01)

Patent

CA 1327576

ABSTRACT OF THE DISCLOSURE The invention concerns novel phenoxyacetic acid amide derivatives of the formula I Image I (and pharmaceutically acceptable salts thereof) in which R1 is hydrogen or fluoro, R2 is phenyl, cycloalkyl, alkyl or alkenyl as defined herein, and R3 is hydrogen, methyl or ethyl, or R2 and R3 together form polymethylene as defined herein. The invention also includes pharmaceutical compositions containing the amide derivatives, means for the manufacture of the said derivatives and for their use in the treatment of obesity and related conditions and/or in the manufacture of novel medicaments.

542721

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