Phenoxyether derivatives as ppar modulators

Details Phenoxyether derivatives as ppar modulators Phenoxyether derivatives as ppar modulators

C - Chemistry, Metallurgy

07

C

C07C 53/134 (2006.01) A61K 31/19 (2006.01) A61K 31/21 (2006.01) A61K 31/435 (2006.01) A61P 3/10 (2006.01) C07C 59/135 (2006.01) C07D 213/30 (2006.01) C07D 213/64 (2006.01) C07D 213/643 (2006.01) C07D 213/69 (2006.01) C07D 239/26 (2006.01)

Patent

CA 2541751

The present invention is directed to a compound of formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR), such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.

La présente invention concerne un composé représenté par la formule (I) ou un sel, un solvate, un hydrate ou des stéréo-isomères de ce composé répondant aux normes pharmaceutiques. Ce composé convient pour traiter ou prévenir des troubles induits par un récepteurs activés de la prolifération des péroxyzomes (PPAR), tels que le syndrome X, le diabète de type II, l'hyperglycémie, d'hyperlipidémie, l'obésité, la coagulopathie, hypertension, l'artériosclérose et d'autres pathologies liées au syndrome X ainsi que des maladies cardio-vasculaires.

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