F - Mech Eng,Light,Heat,Weapons – 28 – B
Patent
F - Mech Eng,Light,Heat,Weapons
28
B
260/557, 260/603
F28B 1/02 (2006.01) F28B 1/00 (2006.01)
Patent
CA 1037968
Abstract of the Disclosure Novel phenoxyethylamine derivatives of the formula: Image (I) wherein R1 and R2 are each hydrogen, halogen, C1-C4 alkyl or C1-C4 alkoxy, R3 is hydrogen or C1-C4 alkyl, R4 and R5 are each hydrogen or C1-C4 alkoxy and R is C1-C4 alkyl or benzyl, and non-toxic pharmaceutically acceptable acid addition salts and N-acetyl derivatives thereof, are disclosed which are useful as central nervous system depressants and anti-hypertensive agents. The novel compounds can be prepared, for example, by reducing a compound of the formula: Image (II) wherein R1, R2, R4, R5 and R are each as defined above and A is -CO-?-CH2- or -CH2-?-CO- (wherein R3 is as defined above).
212044
Katayama Shigenari
Maruyama Isamu
Nakao Masaru
Sasajima Kikuo
Yamamoto Hisao
Na
Sumitomo Chemical Company
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