Phenoxyphenylacetic acid derivatives

Details Phenoxyphenylacetic acid derivatives Phenoxyphenylacetic acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 317/46 (2006.01) A61K 31/19 (2006.01) A61K 31/33 (2006.01) C07C 59/68 (2006.01) C07C 59/70 (2006.01) C07C 65/24 (2006.01) C07C 311/51 (2006.01) C07D 257/04 (2006.01) C07D 317/60 (2006.01) C07D 317/64 (2006.01) C07D 319/18 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2119051

TITLE OF THE INVENTION PHENOXYPHENYLACETIC ACID DERIVATIVES ABSTRACT OF THE INVENTION Phenoxyphenylacetic acids and derivatives of the general structural formula I Image I have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.

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