Phenoxypropanolamines

C - Chemistry – Metallurgy – 07 – D

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260/602.3, 260/5

C07D 295/096 (2006.01) C07D 277/34 (2006.01)

Patent

CA 1065894

Abstract of the Disclosure This invention relates to compounds of the formula I Image (I) wherein R1 is selected from the group consisting of hydrogen and methyl and R2 is selected from the group consisting of hydrogen, methyl, ethyl, propyl, allyl, methoxy, propargyloxy, cyano, morpholino, pyrrolidino and pyrrolyl R3 is selected from the group consisting of hydrogen, methyl and ethyl, and R4 is selected from the group consisting of hydrogen and methyl, provided that R2 ant R4 are not both hydrogen. These compounds are prepared according to known methods. They are useful in the treatment of cardiovascular disorders, including arrythmias, angina pectoris and hypertension.

238765

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