C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/20 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/427 (2006.01) C07C 69/734 (2006.01) C07C 217/76 (2006.01) C07C 233/66 (2006.01) C07C 235/60 (2006.01) C07C 271/48 (2006.01) C07C 271/58 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 213/20 (2006.01) C07D 213/30 (2006.01) C07D 277/34 (2006.01)
Patent
CA 2472209
Formula (I) compounds are described: Where the groups are as defined here below, and their use as medinies, particularly as serum glucose and serum lipid lowering agents. Said medicines are useful for the prophylaxis and treatment of diabetes, particularly type 2, and its complications, Syndrome X, the various forms of insulin resistance, and hyperlipidaemias, and present reduced side effects, and, particularly, reduced or no liver toxicity.
L'invention concerne des composés représentés par la formule (I) dont les groupes sont définis ci-dessous et leur utilisation comme médicaments, en particulier comme agents d'abaissement de glucose et de lipides sériques. On utilise ces médicaments pour la prophylaxie et le traitement du diabète (notamment du type 2) et ses complications, du syndrome X, des différentes formes de résistance à l'insuline et de l'hyperlipidémie. Lesdits médicaments présentent peu d'effets secondaires et sont peu ou ne sont pas toxiques pour le foie.
Arduini Arduino
Brunetti Tiziana
Dell'uomo Natalina
Giannessi Fabio
Pessotto Pompeo
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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