Phenyalkylamines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 295/04 (2006.01) C07D 207/06 (2006.01) C07D 207/20 (2006.01) C07D 211/12 (2006.01) C07D 211/14 (2006.01) C07D 211/16 (2006.01) C07D 213/16 (2006.01) C07D 295/096 (2006.01) C07D 295/112 (2006.01) C07D 295/135 (2006.01) C07D 309/12 (2006.01) C07D 491/10 (2006.01) C07D 493/10 (2006.01)

Patent

CA 1053251

ABSTRACT OF THE DISCLOSURE N-{3-[R1-(phenyl)-C(=X)]-phenyl-lower-alkyl}aminess, wherein R1 is hydrogen or 1 or 2 substituents -C(=X) represents Image , Image , Image , Image , Image or Image and R3 is hydrogen or lower-alkyl, having anti-inflammatory utility are prepared either by reduction of a 3-[R1-(phenyl)-CO]-phenyl-lower- alkanoylamine; by benzoylating a phenyl-lower-alkylamine; by reaction of a 3-lithio-phenyl-lower-alkylamine with a R1-(phenyl)- carboxaldehyde, a R1-(phenyl)lower-alkyl ketone or a R1-(phenyl)- carbonitrile or by transformations involving manipulations of a carbonyl or carbinol group.

243670

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