Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 413/12 (2006.01) A61K 31/4245 (2006.01)

Patent

CA 2624105

The invention relates to phenyl-[1 ,2,4]-oxadiazol-5-one derivatives with phenyl group in all its stereoisomeric forms and mixtures in any ratio, and its physiologically acceptable salts and tautomeric forms showing PPARdelta agonist activity. What is described are compounds of the formula (I), wherein the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.

L'invention concerne des dérivés de phényl-[1,2,4]-oxadiazol-5-one à groupe phényle sous toutes leurs formes stéréoisomères et leurs mélanges dans des proportions quelconques, ainsi que les sels physiologiquement acceptables et les formes tautomères de ceux-ci qui exercent une activité agoniste sur les récepteurs PPAR.DELTA.. L'invention décrit ainsi des composés représentés par la formule (I), dans laquelle les radicaux sont tels que définis dans la description, ainsi que les sels physiologiquement acceptables de ceux-ci et les procédés utilisés pour les obtenir. Ces composés sont utilisés pour traiter et/ou prévenir les troubles du métabolisme des acides gras, les troubles de l'utilisation du glucose, les troubles impliquant l'insulinorésistance et la démyélinisation, ainsi que d'autres troubles neurodégénératifs du système nerveux central et périphérique.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1866414

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.