Phenyl-prenyl derivatives, of marine and synthetic origin,...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 43/20 (2006.01) C07C 47/228 (2006.01) C07C 69/614 (2006.01) C07C 69/708 (2006.01) C07C 233/53 (2006.01)

Patent

CA 2714422

The present invention is related to a family of phenyl-prenyl derivatives of formula (I), and to their use in the treatment of cognitive, neurodegenerative or neuronal diseases or disorders, such as Alzheimer's disease or Parkinson's Disease. The present invention also relates to pharmaceutical compositions comprising the same. Further, the present invention is directed to the compounds of formula (I) for medical use, particularly for the use for the treatment and/or prevention of a cognitive, neurode-generative or neuronal disease or disorder, and to the use of the compounds in the manufacture of a medicament for the treatment and/or prevention of a cognitive, neurodegenerative or neuronal disease or disorder.

L'invention concerne une famille de dérivés de phényle-prényle de la formule (I) et l'utilisation desdits dérivés dans le traitement de maladies ou troubles cognitifs, neurodégénératifs ou neuronaux, comme la maladie d'Alzheimer ou la maladie de Parkinson. L'invention porte également sur des compositions pharmaceutiques comprenant ces dérivés. L'invention se rapporte aussi à des composés de la formule (I) à usage médical, destinés en particulier au traitement et/ou à la prévention d'une maladie ou d'un trouble cognitif, neurodégénératif ou neuronal, et à l'utilisation desdits composés dans la fabrication d'un médicament destiné au traitement et/ou à la prévention d'une maladie ou d'un trouble cognitif, neurodégénératif ou neuronal. Formule (I).

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