C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/272
C07D 455/02 (2006.01) C07D 211/76 (2006.01)
Patent
CA 1142933
RAN 4085/4 ABSTRACT Phenyl-quinolizidines of the general formula Image wherein X, Y and R1 have the following significance: X: hydrogen, fluorine, chlorine, lower-alkoxy, lower-alkyl or trifluoromethyl, Y: hydrogen, fluorine, chlorine, lower-alkoxy or lower-alkyl, R1: acyl, acylamino or a group A of the formula or A Image Image wherein R2-R5 have the following significance R2: oxygen or sulphur, R3: hydrogen or lower-alkyl, R4 and R5: one is hydrogen and the other is bromine, iodine, cyano, lower-alkoxy- carbonyl or sulphamoyl, in the form of the racemate or of the enantiomers, and acid addition salts of such compounds. Further, also corresponding pharmaceutical preparations, the manufacture of the active substances, corresponding starting materials as well as the use of the active substances in controlling illnesses.
374633
Imhof Rene
Kyburz Emilio
Fetherstonhaugh & Co.
Hoffmann-La Roche Limited
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