C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/36 (2006.01) A61K 31/501 (2006.01) A61K 31/52 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 403/02 (2006.01) C07D 403/04 (2006.01) C07D 471/04 (2006.01) C07D 473/26 (2006.01) C07D 473/32 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2484631
Compounds described by the formula (I) or formula (II): (I), (II), or pharmaceutically acceptable salts thereof, are inhibitors of p38 useful in the treatment of inflammatory diseases such as arthritis. Compounds may be selective adenosine A1 antagonists useful in the treatment of neurological disorders such as dementia and depression.
les composés représentés par la formule (I) ou la formules (II): (I), (II) ou des sels de ces composés répondants aux normes pharmaceutiques, sont des inhibiteurs de p38 qui conviennent pour le traitement de maladies inflammatoires telles que l'arthrite. Ces composés peuvent être des antagonistes A1 d'adénosine sélectifs qui conviennent pour le traitement de troubles neurologiques tels que la démence et la dépression.
Beresis Richard
Colletti Steven L.
Doherty James Burke
Zaller Dennis M.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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