Phenyl sulfoxides and phenyl sulfones

Details Phenyl sulfoxides and phenyl sulfones Phenyl sulfoxides and phenyl sulfones

A - Human Necessities

61

K

A61K 31/10 (2006.01) A61K 31/40 (2006.01) A61K 31/4409 (2006.01) A61K 31/4465 (2006.01) A61K 31/496 (2006.01) A61K 31/5375 (2006.01) A61P 25/28 (2006.01) C07C 317/18 (2006.01) C07C 317/22 (2006.01) C07D 207/06 (2006.01) C07D 207/46 (2006.01) C07D 211/22 (2006.01) C07D 211/46 (2006.01) C07D 211/52 (2006.01) C07D 213/74 (2006.01) C07D 239/42 (2006.01) C07D 241/08 (2006.01) C07D 295/20 (2006.01) C07D 295/205 (2006.01) C07D 491/10 (2006.01) C07D 493/10 (2006.01)

Patent

CA 2473374

The invention relates to the phenyl sulfoxides and phenyl sulfones of formula (I) and to methods for producing the same as well as to their use in the production of drugs for the treatment and/or prophylaxis of diseases, especially Alzheimer's disease. The inventive compounds inhibit .gamma. secretase.

L'invention concerne de l'oxyde sulfonique de phényle ou des sulfones de phényle de formule (I), leur procédé de production et leur utilisation dans la production de médicaments pour le traitement et/ou la prophylaxie de maladies, en particulier la maladie d'Alzheimer. Lesdits composés de l'invention inhibent la .gamma.-sécrétase.

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