Phenylacetamido-thiazole derivatives, process for their...

Details Phenylacetamido-thiazole derivatives, process for their... Phenylacetamido-thiazole derivatives, process for their...

C - Chemistry, Metallurgy

07

C

C07C 49/00 (2006.01) C07D 277/46 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2453294

Compounds represented by formula (I), as defined in the description, wherein R is a hydrogen atom or a methyl group and R1 is a group as defined in the specification, or a pharmaceutically acceptable salt thereof, are disclosed; the said compounds are useful in the treatment of cell proliferative disorders, e.g. cancer, associated with an altered cell cycle dependent kinase activity.

La présente invention concerne des composés représentés par la formule (I), tels que définis dans la description de cette invention, dans laquelle R représente un atome d'hydrogène ou un groupe méthyle et R¿1? représente un groupe tel que défini dans la description ou un sel de celui-ci, acceptable d'un point de vue pharmaceutique. Ces composés sont utilisés pour traiter des troubles de la prolifération cellulaire, tels que le cancer, qui sont associés à une activité de kinase modifiée dépendant du cycle cellulaire.

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