Phenylacetic acid derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 61/16 (2006.01) C07C 1/22 (2006.01) C07C 45/46 (2006.01) C07C 49/792 (2006.01) C07C 49/813 (2006.01) C07C 51/08 (2006.01) C07C 51/36 (2006.01) C07C 51/367 (2006.01) C07C 51/377 (2006.01) C07C 51/38 (2006.01) C07C 51/41 (2006.01) C07C 57/46 (2006.01) C07C 57/62 (2006.01) C07C 59/86 (2006.01) C07C 61/40 (2006.01) C07C 62/36 (2006.01) C07C 62/38 (2006.01) C07C 69/76 (2006.01) C07D 263/10 (2006.01) C07D 263/12 (2006.01)

Patent

CA 1127177

ABSTRACT OF THE DISCLOSURE Indane-1-carboxylic acid derivatives of the general formula I Image (I), wherein n represents the numbers 2 to 5, ?A-B- represents the groupings ?CH-CH2-, ?C=CH- or ?CH-CO- R1 represents a hydrogen atom, a halogen atom, a trifluoromethyl group, a nitro group or an amino group, X1 represents two hydrogen atoms or an oxo group, and Y represents a cyano group, a hydroxyamidocarbonyl group, a car- bamoyl group, a carboxyl group, a salt thereof with physiologi- cally tolerable bases, an ester thereof with physiologically tolerable alcohols or an amide thereof with physiologically tol- erable amines. The compounds are pharmacologically active com- pounds with a pronounced anti-inflammatory activity, or inter- mediates, and can be made up into pharmaceutical preparations.

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