Phenylalkylcarboxylic acid derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/55 (2006.01) A61K 31/19 (2006.01) A61K 31/33 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) C07C 251/54 (2006.01) C07C 251/58 (2006.01) C07C 251/60 (2006.01) C07C 317/32 (2006.01) C07C 323/45 (2006.01) C07C 323/62 (2006.01) C07D 207/337 (2006.01) C07D 213/53 (2006.01) C07D 213/64 (2006.01) C07D 213/70 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01)

Patent

CA 2251468

Phenylalkylcarboxylic acid derivatives represented by general formula (I) and pharmacologically acceptable salts and esters thereof (wherein R1 represents alkyl, etc.; R2 represents alkylene; R3 represents hydrogen, etc.; X represents (un)substituted aryl, etc.; Y represents oxygen, etc.; Z represents alkylene, etc.; and W represents alkyl, etc.), useful as a remedy or preventive for hyperglycemia and the like.

L'invention concerne des dérivés d'acide phénylalkylcarboxylique représentés par la formule générale (I), ainsi que leurs sels et esters pharmacologiquement acceptables. Dans ladite formule (I), R?1¿ représente alkyle etc.; R?2¿ représente alkylène; R?3¿ représente hydrogène, etc.; X représente aryle substitué ou non-substitué etc.; Y représente oxygène etc.; Z représente alkylène, etc.; et W représente alkyle etc.. Ces dérivés, ou leurs sels et esters pharmacologiquement acceptables, peuvent être utilisés pour traiter ou prévenir l'hyperglycémie ou un état pathologique analogue.

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