C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/70 (2006.01) A61K 31/505 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 491/056 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2258548
The invention relates to compounds of formula (I) and to pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, n and Z are as defined herein. The compounds of formula (I) are useful in the treatment of hyperproliferative disorders, such as cancer. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of treating hyperproliferative disorders using the compounds of formula (I).
Composés de la formule (I), dans laquelle R<1>, R<2>, R<3>; R<4>, n et Z sont tels que définis, et leurs sels pharmaceutiquement acceptables. Les composés de la formule I sont utiles pour le traitement des troubles hyperprolifératifs, tels que le cancer. L'invention se rapporte également à des compositions pharmaceutiques contenant les composés de la formule (I), ainsi qu'à des procédés de traitement de troubles hyperprolifératifs au moyen desdits composés.
Pfizer Inc.
Smart & Biggar
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