Phenylcarboxylate beta-secretase inhibitors for the...

A - Human Necessities – 61 – K

Patent

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A61K 31/18 (2006.01) A61K 31/235 (2006.01) A61K 31/24 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07C 63/00 (2006.01) C07C 303/00 (2006.01) C07D 207/18 (2006.01) C07D 211/06 (2006.01)

Patent

CA 2530006

The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.

La présente invention concerne des composés qui sont inhibiteurs de l'enzyme béta-secrétase et utiles pour traiter les maladies dans lesquelles l'enzyme béta-secrétase est impliquée, telles que la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques contenant ces composés et l'utilisation de ces composés et compositions dans la prévention ou le traitement des maladies dans lesquelles l'enzyme béta-secrétase est impliquée.

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