Phenylene furyl, and thienyl leukotriene b_ analogues

Details Phenylene furyl, and thienyl leukotriene b_ analogues Phenylene furyl, and thienyl leukotriene b_ analogues

C - Chemistry, Metallurgy

07

C

167/179, 260/552

C07C 59/48 (2006.01) C07C 69/732 (2006.01) C07D 307/54 (2006.01) C07D 309/30 (2006.01) C07D 333/24 (2006.01)

Patent

CA 1325809

ABSTRACT This invention related to leukotriene B4 antagonists having the structure Image and the pharmaceutically acceptable addition salts thereof; wherein R1 is lower alkyl having 1-10 carbon atoms; or lower alkenyl or alkynyl having 2-10 carbon atoms; or lower alkadienyl having 3-10 carbon atoms; or lower alkadienyl or alkenynyl having 4-10 carbon atoms; wherein R2 and R3 are the same or different and represent hydrogen or lower alkyl having 1-6 carbon atoms; wherein X is CH=CH, S, or O; wherein Y is CH=CH or C?C; wherein Z is OR4 or NR5R6, and wherein R4 represents H, lower alkyl having 1-6 carbon atoms, or a pharmaceutically acceptable cation, and wherein R5 and R6 act independently and represent H or lower alkyl having 1-6 carbon atoms, or R5 and R6 may act together with N to form a cycloamine of the formula: Image wherein q is an integer from 2-5; wherein m and n are the same or different and either 1 or 0; and wherein p is an integer from 1 to 5.

570178

Affiliated with

Also associated with

Rating

Phenylene furyl, and thienyl leukotriene b_ analogues does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phenylene furyl, and thienyl leukotriene b_ analogues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenylene furyl, and thienyl leukotriene b_ analogues will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1262043