A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/137 (2006.01)
Patent
CA 2709208
Pharmaceutical compositions comprising phenylephrine or a pharmaceutically acceptable salt thereof and methods for administering the pharmaceutical compositions wherein the composition is formulated for systemic absorption of phenylephrine that avoids first pass metabolism. The compositions of the invention are formulated to be applied to oral mucosa of an animal to allow for enhanced systemic delivery of therapeutically active form of phenylephrine.
La présente invention concerne des compositions pharmaceutiques comprenant de la phényléphrine ou un sel pharmaceutiquement acceptable de celle-ci. L'invention porte également sur des procédés d'administration desdites compositions pharmaceutiques, ces compositions étant formulées pour permettre l'absorption systémique de phényléphrine, ce qui évite le métabolisme de premier passage hépatique. Les compositions de la présente invention sont formulées pour être appliquées à la muqueuse orale d'un animal, en vue de permettre l'amélioration de l'administration systémique de la forme de phényléphrine thérapeutiquement active.
Chen Xiaoming
Kabir Mohammed A.
Monteith David
Nelson Dennis
O'mullane John
Msd Consumer Care Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering-Plough Healthcare Products Inc.
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