Phenylguanidine acetylsalicylate compounds, process for...

Details Phenylguanidine acetylsalicylate compounds, process for... Phenylguanidine acetylsalicylate compounds, process for...

C - Chemistry, Metallurgy

07

C

260/489.3, 260/4

C07C 129/12 (1980.01)

Patent

CA 1182835

Abstract of the Disclosure A compound of the formula Image wherein R1 is a member selected from the group consisting of a hydrogen atom, lower alkyl groups and lower alkoxy groups, R2 is a member selected from the group consisting of a hydrogen atom, halogen atoms, lower alkyl groups, a hydroxyl group and a trifluoromethyl group, R3 is a member selected from the group consisting of a hydrogen atom, halogen atoms, lower alkyl groups, lower alkoxy groups, an acetyl group, a carbamoyl group and lower alkyl carboxylate groups, and R3 represents a hydrogen atom or a halogen atom. The phenylguanidine acetylsalicylate compounds are prepared by reacting a corresponding guanidine compound with acetyl- salicylic acid and are useful as antipyretic-analgesic agents, anti- inflammatory agents, platelet aggregation inhibitors and prostaglandin formation inhibitors.

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