Phenylindoles for the treatment of hiv

Details Phenylindoles for the treatment of hiv Phenylindoles for the treatment of hiv

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/404 (2006.01) A61K 31/5377 (2006.01) A61P 31/18 (2006.01) C07D 209/42 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2444501

The invention as disclosed herein is a method and composition for the treatment of HIV in humans and other host animals, that includes the administration of an effective HIV treatment amount of a phenylindole as described herein or a pharmaceutically acceptable salt or prodrug thereof, optionally in a pharmaceutically acceptable carrier. The compounds of this invention either possess antiviral (i.e., anti-HIV) activity, or are metabolized to a compound that exhibits such activity. (see above formula)

La présente invention se rapporte à une méthode et à une composition pour le traitement de l'infection par le VIH chez des humains et autres animaux hôtes. La méthode consiste en l'administration d'une quantité suffisante pour traiter efficacement une infection par le VIH d'un phénylindole tel que celui indiqué dans la description ou d'un sel ou promédicament pharmaceutiquement acceptable de ce phénylindole, éventuellement dans un excipient pharmaceutiquement acceptable. Les composés de cette invention peuvent soit posséder une activité antivirale (c'est-à-dire, anti-VIH), soit être métabolisés en un composé qui présente une telle activité.

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