C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/10 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2200433
A compound of structural formula (I), or pharmaceutically acceptable salts thereof wherein: Q is selected from the structures i, ii, iii, iv and v. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, particularly aerobic gram-positive bacteria, including multiply-resistant staphylococci, enterococci and streptococci, as well as anaerobic organisms such as bacteroids and clostridia species, and acid-fast bacteria such as as Mycobacterium tuberculosis and other mycobacterial species.
Composé représenté par la formule développée (I), ou ses sels acceptables pharmaceutiquement, dans laquelle: Q est sélectionné à partir des structures i, ii, iii, iv et v. Ces composés sont des agents antimicrobiens efficaces contre plusieurs agents pathogènes de l'homme et de l'animal, en particulier des bactéries aérobies à Gram positif, y compris des staphylocoques, des entérocoques et des streptocoques multirésistants, ainsi que des organismes anaérobies, tels que des bactéroïdes et des espèces clostridia et des bactéries acido-résistantes, telles que Mycobacterium tuberculosis et d'autres espèces mycobactériennes.
Barbachyn Michael R.
Brickner Steven J.
Hutchinson Douglas K.
Munesada Kiyotaka
Taniguchi Mikio
Macrae & Co.
Pharmacia & Upjohn Company
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