Phenylpiperidine derivative

Details Phenylpiperidine derivative Phenylpiperidine derivative

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/445 (2006.01) A61K 31/55 (2006.01) C07D 211/52 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/044 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2231773

Phenylpiperidine derivative represented by general formula (I) or pharmacologically acceptable salts thereof and an analgetic agent containing the compound, wherein X represents CH or N: Y-Z represents CH2-O, CH2-S, CH2- CH2, CH=CH or CONR5 (wherein R5 represents hydrogen or lower alkyl); R1 represents hydrogen, lower alkyl, halogeno, lower alkoxy or trifluoromethyl; and R2, R3 and R4 are the same or different and each represents hydrogen, lower alkyl or QR6 (wherein Q represents a single bond or lower alkylene; and R6 represents hydroxy, lower alkoxyalkoxy, lower alkoxy, lower alkylthio, nitro, halogeno, lower alkanoyloxy, lower alkoxycarbonyl, lower alkanoyl or carboxy.

La présente invention concerne un dérivé de phénylpipéridine représenté par la formule générale (I) ou des sels de cette substance acceptables en pharmacie, et un agent analgésique contenant ce composé. Dans cette formule, X représente CH ou N; Y-Z représente CH¿2?-O, CH¿2?-S, CH¿2?-CH¿2?, CH=CH ou CONR?5¿ (R?5¿ étant hydrogène ou alkyle inférieur); R?1¿ représente hydrogène, alkyle inférieur, halogéno, alcoxy inférieur ou trifluorométhyle, et R?2¿, R?3¿ et R?4¿ sont identiques ou non et représentent chacun hydrogène, alkyle inférieur ou QR?6¿ (Q étant une liaison simple ou alkylène inférieur, et R?6¿ représentant hydroxy, alcoxyalcoxy inférieur, alcoxy inférieur, alkylthio inférieur, nitro, halogéno, alcanoyloxy inférieur, alcoxycarbonyle inférieur, carboxy ou alcanoyle inférieur.

Affiliated with

Also associated with

Rating

Phenylpiperidine derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phenylpiperidine derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenylpiperidine derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1898396