Phenylthioacetic acid derivatives and use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/12 (2006.01) A61K 31/4155 (2006.01) A61K 31/4178 (2006.01) A61K 31/4192 (2006.01) A61K 31/42 (2006.01) A61K 31/421 (2006.01) A61K 31/4245 (2006.01) A61K 31/427 (2006.01) C07D 231/12 (2006.01) C07D 231/28 (2006.01) C07D 263/32 (2006.01) C07D 271/06 (2006.01) C07D 277/28 (2006.01) C07D 405/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2562140

The invention relates to novel phenylthioacetic acid derivatives of formula (I), to a method for the production thereof, to the use thereof for the treatment and/or prophylaxis of diseases, in addition to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prevention of cardiovascular diseases, in particular dyslipidaemia and arteriosclerosis. The compounds act as modulators for the PRAR-alpha receptor.

L'invention concerne de nouveaux dérivés d'acide phénylthioacétique de formule (I), des procédés pour leur production, leur utilisation pour traiter et/ou prévenir des maladies, ainsi que leur utilisation pour produire des médicaments servant à traiter et/ou à prévenir des maladies, de préférence à traiter et/ou à prévenir des maladies cardio-vasculaires, notamment des dyslipidémies et l'artériosclérose. Les composés selon l'invention agissent comme modulateurs du récepteur PPAR-alpha.

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