Phosphadiazine hcv polymerase inhibitors iv

Details Phosphadiazine hcv polymerase inhibitors iv Phosphadiazine hcv polymerase inhibitors iv

C - Chemistry, Metallurgy

07

F

C07F 9/6584 (2006.01) A61K 31/675 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2697546

Provided herein are phosphadiazine polymerase inhibitor, for example, of any of Formulas (IV), (IV), (I"), (II"), or (IVa), pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.

L'invention concerne des inhibiteurs de la phosphadiazine polymérase, par exemple, représentés par n'importe laquelle des formules IV, IV, I", II", ou IVa, des compositions pharmaceutiques comprenant lesdits composés, ainsi que leurs procédés de préparation. L'invention concerne également leurs méthodes d'utilisation pour le traitement d'une infection par le VHC chez un hôte nécessitant un tel traitement.

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