Phosphate buffer in toothpaste with high level of humectant

Details Phosphate buffer in toothpaste with high level of humectant Phosphate buffer in toothpaste with high level of humectant

A - Human Necessities

61

K

167/318.1

A61K 8/24 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 1145677

Abstract Fluoride toothpastes are described which contain a high level of humectant, a silica abrasive and a fluoride ion source and which have superior fluoride and flavor stability. They comprise (A) from about 6% to 45% of a silica dental abrasive; (B) from about 30% to 70% of a humectant; (C) from about 0.01% to 3% of a fluoride ion source; and (D) from about 10% to 45% of water; said composition additionally containing an amount of a phos- phate buEfering agent providing from about 0.1% to 1% PO4-3, the amount being sufficient to maintain the pH of a 3:1 water/composition weight ratio slurry in the range of about 6.8 to 8Ø

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