Phosphate derivatives as immunoregulatory agents

Details Phosphate derivatives as immunoregulatory agents Phosphate derivatives as immunoregulatory agents

C - Chemistry, Metallurgy

07

F

C07F 9/09 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2421893

Immunoregulatory compounds are disclosed of the formula: and as well as the pharmaceutically acceptable salts and hydrates thereof, are disclosed. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

L'invention concerne des composés immuno-régulateurs de formule 1 et A, ainsi que des sels et des hydrates pharmaceutiquement acceptables de ces derniers. Les composés sont utiles dans le traitement de maladies et de conditions d'origine immunologique, telles que le rejet de greffes de moëlle osseuse, d'organes ou de tissus. L'invention concerne également des compositions pharmaceutiques et des procédés d'utilisation.

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