Phosphate-modified oligonucleotide analogs with enhanced...

Details Phosphate-modified oligonucleotide analogs with enhanced... Phosphate-modified oligonucleotide analogs with enhanced...

A - Human Necessities

61

K

A61K 31/7125 (2006.01) A61K 45/06 (2006.01) A61P 11/06 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2687535

The invention relates to oligonucleotides including at least one backbone modification and a pyrimidine-purine dinucleotide. The invention also relates to pharmaceutical compositions and methods of use thereof.

L'invention porte sur des oligonucléotides comprenant au moins une modification de squelette et un dinucléotide pyrimidine-purine. L'invention porte également sur des compositions pharmaceutiques et sur leurs procédés d'utilisation.

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