A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/40 (2006.01) C07F 9/572 (2006.01)
Patent
CA 2479256
The present invention provides novel phosphate derivatives having the general Formula (I) wherein the wavy bond (b) represents the racemate, the (R)- enantiomer or the (S)-enantiomer and A, B, R1, R2, R3, R4, m and n are as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are responsive to the opening of potassium channels.
La présente invention concerne des nouveaux dérivés de phosphate représentés par la formule générale (I); dans cette formule, la liaison ondulée (b) représente le racémate, le (R)-énantiomère ou le (S)-énantiomère, et A, B, R?1¿, R?2¿, R?3¿, R?4¿, m et n sont tels que définis dans la description, ou un sel non toxique pharmaceutiquement acceptable ou un solvate de ceux-ci. Ces dérivés sont utilisés pour traiter des troubles sensibles à l'ouverture des canaux potassium.
Gillman Kevin W.
Hewawasam Piyasena
Lopez Omar D.
Provencal David P.
Schmitz William D.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
Phosphate prodrugs of fluorooxindoles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phosphate prodrugs of fluorooxindoles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phosphate prodrugs of fluorooxindoles will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1580913