Phosphatidyl-3,4,5-triphosphate-dependent protein kinase

Details Phosphatidyl-3,4,5-triphosphate-dependent protein kinase Phosphatidyl-3,4,5-triphosphate-dependent protein kinase

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2284119

A substantially pure 3-phosphoinositide dependent protein kinase that phosphorylates and activates protein kinase B.alpha.. A recombinant polynucleotide encoding a protein kinase as defined. Uses of the protein kinase and polynucleotide, especially in screening for new drugs.

Protéine kinase, à activité dépendante d'un 3-phosphoinositide sensiblement pur, qui phosphoryle et active la protéine kinase B.alpha.. L'invention concerne également un polynucléotide recombinant codant une protéine kinase, telle que définie dans les revendications, ainsi que les utilisations de la protéine kinase et du polynucléotide, en particulier lors du triage de nouveaux médicaments.

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