Phosphodiesterase 4 inhibitors, including n-substituted...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/38 (2006.01) A61K 31/44 (2006.01) A61P 25/00 (2006.01) C07C 217/88 (2006.01) C07C 217/92 (2006.01) C07C 229/60 (2006.01) C07D 215/14 (2006.01) C07D 217/18 (2006.01) C07D 241/12 (2006.01) C07D 261/08 (2006.01) C07D 277/28 (2006.01) C07D 333/20 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2492907

PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula (I): wherein R1, R2 R 3 and R4 are as defined herein.

De nouveaux composés inhibent la phosphodiestérase 4 (PDE4), par exemple des analogues de diphénylamine et d'aniline N-substitués. Les composés de cette invention sont représentés par la formule I: R?1¿, R?2¿ R ?3¿ et R?4¿ étant tels que définis dans les spécifications.

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