Phosphoepoxides, method for making same and uses

C - Chemistry – Metallurgy – 07 – F

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C07F 9/655 (2006.01) C12N 5/0783 (2010.01) A61K 31/665 (2006.01) A61K 35/14 (2006.01) C07H 19/10 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2341578

The invention concerns compounds comprising at least a phosphoepoxide group of formula (I) wherein: R1 is selected among -CH¿3? and -CH¿2?-CH¿3?; Cat+ is an organic or mineral cation; n is an integer between 2 and 20. The invention also concerns their preparation methods and applications, in particular in therapy for activating T.gamma.9.delta.2 lymphocytes of primates.

L'invention concerne des composés comprenant au moins un groupement phosphoépoxyde de formule (I) où R1 est choisi parmi -CH3 et -CH2-CH3, Cat+ est un cation organique ou minéral, n est un nombre entier compris entre 2 et 20, leurs procédés de préparation, et leurs applications, notamment thérapeutiques et pour activer les lymphocytes T.gamma.9.delta.2 des primates.

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