Phosphoglycan messengers and their medical uses

Details Phosphoglycan messengers and their medical uses Phosphoglycan messengers and their medical uses

C - Chemistry, Metallurgy

07

G

C07G 3/00 (2006.01) A61K 31/70 (2006.01) A61P 3/00 (2006.01) C07H 1/08 (2006.01) C07H 15/207 (2006.01)

Patent

CA 2427742

Phosphoglycan messengers (PGMs) which are carbohydrate derivatised phosphatidyl cyclitols are disclosed, together with the finding that these substances are biologically active, e.g. in lowering blood glucose levels. These compounds are distinct from GPI-anchors disclosed in the prior art as these GPI-anchors are protein linked and are not biologically active.

L'invention concerne des messagers phosphoglycane (PGM) qui sont des phosphatidyl cyclitols dérivés de glucides, ainsi que la découverte selon laquelle ces matières sont biologiquement actives, p. ex dans la réduction du taux de glycémie. Ces composés se distinguent d'ancres GPI divulguées précédemment en ce que lesdites ancres GPI se lient aux protéines et ne sont pas biologiquement actives.

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