Phosphohalohydrins, method for making same and uses

Details Phosphohalohydrins, method for making same and uses Phosphohalohydrins, method for making same and uses

C - Chemistry, Metallurgy

07

F

C07F 9/09 (2006.01) C12N 5/0783 (2010.01) A61K 31/6615 (2006.01) A61K 35/14 (2006.01) A61K 39/00 (2006.01) C07H 19/10 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2341574

The invention concerns compounds comprising at least a phosphohalohydrin group of formula (1) wherein: X is a halogen selected among I, Br, Cl; R1 is selected among -CH¿3? and -CH¿2?-CH¿3?; Cat?+¿ is an organic or mineral cation; and n is an integer ranging between 2 and 20. The invention also concerns their preparation methods and applications, particularly in therapy and for activating T.gamma.9.delta. lymphocytes of primates.

L'invention concerne des composés comprenant au moins un groupement phosphohalohydrine de formule (1), où X est un halogène choisi parmi I, Br, CI, RI est choisi parmi -CH3 et -CH2-CH3, Cat+ est un cation organique ou minéral, et n est un nombre entier compris entre 2 et 20, leurs procédés de préparation et leurs applications, notamment thérapeutiques et pour activer les lymphocytes T.gamma.982 des primates.

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