Phospholane salts and their use in enantioselective...

C - Chemistry – Metallurgy – 07 – F

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C07F 9/6574 (2006.01)

Patent

CA 2524915

Process for preparing a catalyst solution by reacting metal complexes and diphosphines in the presence of an inert organic solvent, which is characterized in that a) an uncharged or cationic metal complex having a TM8 metal as central atom, and b) a salt of a chiral ditertiary diphosphine which has one or two phospholane groups which are bound to a carbon chain having from 2 to 4 carbon atoms and contain anions selected from the group consisting of RCCOO-, RCSO3-, BF4-, PF6-, AsF6-, SbF6-, B(C6F5)4- and B(3,5- bistrifluoromethylphenyt)4-, are reacted with one another, where the ratio of the components a) and b) is from 1 : 1 to 1 : 2 and RC is C1-C6-haloalkyl, C5- C10-~halocycloalkyl or C6-C10-haloaryl.

L'invention a trait à un procédé de préparation d'une solution de catalyseur, qui consiste à faire réagir des complexes métalliques et des diphosphines en présence d'un solvant organique inerte. Ledit procédé est caractérisé en ce que l'on fait réagir : a) un complexe métallique électriquement neutre ou cationique possédant un métal TM8 comme atome central ; avec b) un sel d'une diphosphine ditertiaire chirale qui possède un ou deux groupes phospholane, lesquels sont liés à une chaîne carbonée renfermant de 2 à 4 atomes de carbone et contiennent des anions sélectionnés parmi R<SB>C</SB>COO?-¿, R<SB>C</SB>SO¿3??-¿, BF¿4??-¿, PF¿6??-¿, AsF¿6??-¿, SbF¿6??-¿, B(C¿6?F¿5?)¿4??-¿ et B(3,5-bistrifluorométhylphényl)¿4??-¿. Le rapport des éléments a) et b) est compris entre 1:1 et 1:2, et R<SB>C</SB> représente haloalkyle C¿1?-C¿6?, halocycloalkyle C¿5?-C¿10? ou haloaryle C¿6?-C¿10?.

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