C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) C07K 14/47 (2006.01) C12N 9/12 (2006.01) C12N 9/16 (2006.01) C12Q 1/44 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2259969
Provided are novel phospholipase D DNA and amino acid sequences. The sequences are useful in methods and compositions for identifying phospholipase D mediator molecules which are in turn useful in therapeutic pharmaceutical compositions for treating rheumatoid arthritis, psoriasis, ulcerative colitis, in wound healing and for treating other diseases or conditions characterized by exhibition of an inflammatory response or in the treatment of cancer and other diseases characterized by pathogenic mitogenicity.
Cette invention concerne de nouvelles séquences d'ADN ou aminoacides de la phospholipase D, utiles dans des procédés et des composition permettant d'identifier des molécules médiatrices de la phospholipase D. Ces molécules sont, à leur tour, utiles dans des compositions pharmaceutiques thérapeutiques servant au traitement de la polyarthrite rhumatoïde, du psoriasis, de la recto-colite hémorragique, à la subérification de blessures et au traitement d'autres maladies ou pathologies caractérisées par une réaction inflammatoire, ou encore au traitement du cancer ou d'autres maladies caractérisées par une mitogénicité pathogène.
Engebrecht Joanne
Frohman Michael A.
Morris Andrew J.
Fetherstonhaugh & Co.
Research Foundation Of State University Of New York
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