Phospholipase inhibitors, including multi-valent...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/404 (2006.01) A61K 31/365 (2006.01) A61K 31/437 (2006.01) A61K 31/663 (2006.01) A61K 31/683 (2006.01) A61K 31/685 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2626961

The present invention provides methods and compositions for the treatment of phospholipase-related conditions. In particular, the invention provides a method of treating insulin-related, weight-related conditions and/or cholesterol-related conditions in an animal subject. The method generally involves the administration of a non-absorbed and/or effluxed phospholipase A2 inhibitor that is localized in a gastrointestinal lumen.

La présente invention concerne des méthodes et des compositions pour le traitement d'états liés aux phospholipases. En particulier, l'invention concerne une méthode de traitement d'états liés à l'insuline, liés au poids et/ou liés au cholestérol chez un sujet animal. La méthode consiste généralement à administrer un inhibiteur de phospoholipases A2 non absorbé et/ou résultant d'un écoulement qui est localisé dans une lumière gastro-intestinale.

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