Phospholipid-based pharmaceutical formulations and methods...

Details Phospholipid-based pharmaceutical formulations and methods... Phospholipid-based pharmaceutical formulations and methods...

A - Human Necessities

61

K

A61K 31/397 (2006.01) A01N 25/00 (2006.01) A61K 35/00 (2006.01)

Patent

CA 2603462

Pharmaceutical formulations and methods of producing and using the same are described and claimed. The formulations are dispersions of phospholipids and one or more pharmacologically active compounds, pharmaceutically acceptable salts thereof, or prodrugs thereof. In specific embodiments, the pharmaceutically active compounds are ansamycins and the overall formulation is substantially devoid of medium and long chain triglycerides.

L'invention porte sur des formulations pharmaceutiques et sur leurs procédés de production et d'utilisation. Les formulations sont des dispersions de phospholipides et d'un ou plusieurs composés actifs d'un point de vue pharmacologique, de sels de ceux-ci acceptables d'un point de vue pharmaceutique et de promédicaments de ceux-ci. Selon des formes d'exécution spécifiques, les composés actifs d'un point de vue pharmaceutique sont des ansamycines, et la formulation globale est sensiblement dépourvue de triglycérides à chaîne moyenne et à longue chaîne.

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