Phospholipid-based powders for drug delivery

Details Phospholipid-based powders for drug delivery Phospholipid-based powders for drug delivery

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/127 (2006.01) A61K 9/14 (2006.01) A61K 9/00 (2006.01) A61M 15/00 (2006.01)

Patent

CA 2382133

Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation. The powders are hollow and porous and are preferably administered via inhalation.

L'invention concerne des poudres à base de phospholipides utilisées dans des applications de distribution de médicaments. Ces poudres renferment un cation polyvalent en quantité efficace pour augmenter la température de transition du cristal gel-phase liquide de la particule par rapport aux particules ne renfermant pas ledit cation polyvalent. Les poudres sont creuses et poreuses, et sont de préférence administrées par inhalation.

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