Phospholipid derivative and reactive vesicle-forming agent

Details Phospholipid derivative and reactive vesicle-forming agent Phospholipid derivative and reactive vesicle-forming agent

C - Chemistry, Metallurgy

07

F

C07F 9/547 (2006.01) A61K 9/127 (2006.01) A61K 47/48 (2006.01) C07F 9/6506 (2006.01) C08G 65/332 (2006.01) C08G 65/335 (2006.01)

Patent

CA 2137296

A novel and useful phospholipid derivative to be used for a reactive vesicle-forming agent, which is represented by the following general formula (1): Image in which R1C(=O) and R8C(=O) represent each an aliphatic acyl group, R3 denotes hydrogen atom or methyl group, OA represents an oxyalkylene group of 2 - 4 carbon atoms, n indicates the average addition mole number of added oxyalkylene group and is 1 - 1,000, p is 0 or 1, X represents Image with q and r being each an integer of 0 to 4 or 1 to 4, respectively, and M denotes hydrogen atom or an alkali metal atom. The phospholipid derivative of the invention facilitates the attachment of various functional substances to the ends of (poly)oxyalkylene chains, by way of a covalent bond.

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