Phospholipid drug derivatives

Details Phospholipid drug derivatives Phospholipid drug derivatives

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 31/335 (2006.01) A61K 31/66 (2006.01) A61K 31/675 (2006.01) A61K 31/685 (2006.01) A61K 31/70 (2006.01) A61K 45/00 (2006.01) A61K 47/48 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2266404

Disclosed herein are methods for increasing the bioavailability of pharmaceutical agents by conjugation to phospholipidis. Also disclosed are phospholipid-derivatized steroids, peptides, antibiotics and other biologically active agents and pharmaceutical formulations comprising these compounds.

L'invention concerne des procédés, destinés à accroître la biodisponibilité d'agents pharmaceutiques par conjugaison à des phospholipides. Des stéroïdes, peptides, antibiotiques et autres agents biologiques actifs transformés en dérivés par des phospholipides sont également décrits, ainsi que des formulations pharmaceutiques comprenant ces composés.

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