Phospholipid-targeted thrombolytic agents

Details Phospholipid-targeted thrombolytic agents Phospholipid-targeted thrombolytic agents

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/43 (2006.01) A61K 38/48 (2006.01) A61K 47/48 (2006.01) C07K 14/315 (2006.01) C07K 14/47 (2006.01) C12N 9/72 (2006.01) C12N 11/02 (2006.01) C12N 15/58 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2086437

ABSTRACT Conjugates with an affinity for phospholipids are disclosed. The conjugates comprise a first com- pound having affinity for phospholipids, with a bin- ding constant that is not greater than about 10-7 M and a second compound that lyses thrombi or is a precursor of a compound that lyses thrombi.

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