Phosphonic acid substituted steroids as steroid...

C - Chemistry – Metallurgy – 07 – J

Patent

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167/191, 260/3,

C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01) C07J 61/00 (2006.01) C07J 63/00 (2006.01)

Patent

CA 2005165

ABSTRACT PHOSPHONIC ACID SUBSTITUTED STEROIDS AS STEROID 5.alpha.-REDUCTASE INHIBITORS Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5.alpha.-reductase. Also invented are intermediates used in preparing these compounds.

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