C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
167/191, 260/3,
C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01) C07J 61/00 (2006.01) C07J 63/00 (2006.01)
Patent
CA 2005165
ABSTRACT PHOSPHONIC ACID SUBSTITUTED STEROIDS AS STEROID 5.alpha.-REDUCTASE INHIBITORS Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5.alpha.-reductase. Also invented are intermediates used in preparing these compounds.
Holt Dennis A.
Levy Mark A.
Metcalf Brian W.
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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