Phosphonic acids derivatives as inhibitors of ptp-1b

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/38 (2006.01) A61K 31/66 (2006.01) A61K 31/662 (2006.01) A61K 31/663 (2006.01) A61K 45/00 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01) C07F 9/553 (2006.01) C07F 9/6506 (2006.01) C07F 9/6518 (2006.01) C07F 9/6524 (2006.01) C07F 9/653 (2006.01) C07F 9/6539 (2006.01) C07F 9/6541 (2006.01)

Patent

CA 2344927

The invention encompasses the novel class of compounds represented by formula (I) which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases.

L'invention concerne une nouvelle classe de composés, représentés par la formule (I), qui sont des inhibiteurs de l'enzyme PTP-1B. Elle concerne également des compositions pharmaceutiques et des méthodes permettant de traiter ou de prévenir les maladies ayant pour médiateur la PTP-1B.

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