A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/66 (2006.01) A61K 31/662 (2006.01) A61K 31/675 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2300910
Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
Cette invention se rapporte à des composés thérapeutiques, ainsi qu'aux méthodes associées, qui modulent le dépôt de plaques amyloïdes chez un patient, quel que soit son état clinique. On module le dépôt de plaques amyloïdes en administrant au sujet une quantité efficace d'un composé thérapeutique comportant un groupe phosphonate et un groupe carboxylate, un de ses congénères ou un sel ou un ester pharmaceutiquement acceptable de ce composé. Dans les réalisations préférées, on régule une interaction entre une protéine amyloïdogène et un constituant de membrane basale.
Gorine Boris
Kong Xianqi
Szarek Walter A.
Thatcher Gregory R.j.
Neurochem (international) Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Queen's University At Kingston
LandOfFree
Phosphono-carboxylate compounds for treating amyloidosis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phosphono-carboxylate compounds for treating amyloidosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phosphono-carboxylate compounds for treating amyloidosis will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1524812